When treating hypertension, physicians now have a huge range of drugs from which to choose in formulating a management strategy. This accessible guide helps the busy clinician access specific information on available drugs as components of an integrated care plan.
The Handbook of Hypertension is a comprehensive review of the evidence base for hypertension and associated disease, providing tables, figures, charts, and summaries of principal findings from clinical studies on hypertension – putting vital information within reach of the busy practitioner.
Containing the most recent guidelines for global cardiovascular risk analysis and evidence-based reviews on important new advances and recent trials, consulting the Handbook of Hypertension will save precious time and improve patient care.
Sommario
Abbreviations.
General Introduction .
Introduction.
Hypertension Syndrome.
Vascular Biology.
Functional Endothelium.
Endothelial Dysfunction.
New Treatment Approach.
Hypothesis: Essential Hypertension and End-Organ Damage.
Hypertension Classification and Guidelines Wordwide.
Hypertension in the US.
JNC-7.
NHANES III and IV.
CHS.
ESH-ESC.
ISHIB.
AHA.
BHS/NICE(RCP).
JBS 2.
Global Cardiovascular Risk Calculation.
Secondary Hypertension.
Measurement of Blood Pressure.
Indirect measurement of blood pressure.
Korotkoff Sounds.
Common Mistakes in Blood Pressure Measurement.
Hypertension-Atherosclerotic Syndrome.
Normotensive Hypertension.
Pre-hypertension.
Nonpharmacologic Treatment of Hypertension.
Nutrition.
Nutraceuticals, Vitamins, Minerals and Antioxidants.
DASH I and II Trials.
Specific Recommendations.
Obesity.
Exercise.
Approaches to Selection of Antihypertensive Therapy.
Stepped Care.
Demographics.
Subsets of Hypertension.
Renin Profiling: The Laragh Method.
Hemodynamics in Hypertension.
Hemodynamics: Logical and Preferred Method to Reduce Blood Pressure.
Hemodynamic Effects of Antihypertensive Drugs.
Hypertension-Related End-Organ Damage.
Life Expectancy and Blood Pressure.
Systolic, Diastolic and Pulse Pressure Concepts.
Isolated Systolic Hypertension.
Clinical Hypertension Trials and Antihypertensive .
Drug Therapy .
Completed Trials and Trials in Progress.
Diuretic and Beta-Blocker Trials.
Summary of Clinical Trials with Diuretics.
Summary of Clinical Trials with Beta-Blockers.
Meta-Analysis of Various Clinical Trials.
Comparisons of ACE-Inhibitor therapy with Placebo.
Comparisons of Calcium-antagonist therapy with Placebo.
Comparisons of More Intensive Blood Pressure Lowering Strategies with Less.
Intensive Strategies.
Comparisons of Ace-Inhibitor based Therapy with Diuretic-based or Beta-Blocker Therapy.
Comparisons of Calcium-antagonist-based Therapy with Diuretic or Beta-BlockerTherapy.
Comparisons of Ace-Inhibitor Therapy with Calcium-antagonist Therapy.
Summary of Clinical Trials in Hypertension and Clinical Outcomes.
Health Outcomes Meta-Analysis.
Comparing the CCBs to other Antihypertensive Therapy.
